INCI名称 乙酰基六肽-30
机理
集聚蛋白（agrin）-肌特异性激酶(MuSK )-缔合蛋白(rapsyn)-乙酰胆碱受体(AchR)稳定有序的串联在一起是神经肌肉连接形成的核心。突触运动神经元释放的集聚蛋白可以使MuSK聚集在一起。乙酰基六肽-30阻止集聚蛋白和肌特异性激酶（MuSK）结合，因此MuSK不能激活以及乙酰胆碱受体β组未被磷酸化，而这两步都是乙酰胆碱受体功能性集聚所必须的。由于乙酰胆碱受体功能性集聚被阻止，乙酰胆碱无法引起肌纤维活动，因此降低肌肉收缩，减少表情纹。
The stable and orderly concatenation of aggrin muscle specific kinase (MuSK) associated protein (rapsyn) acetylcholine receptor (AchR) is the core of the formation of neuromuscular connections. The aggregation proteins released by synaptic motor neurons can cause MuSK to aggregate together. Acetylhexapeptide-30 prevents aggregation protein from binding to muscle specific kinase (MuSK), therefore MuSK cannot be activated and acetylcholine receptors cannot be activated β The group is not phosphorylated, and both steps are necessary for the functional aggregation of acetylcholine receptors. Due to the blocking of functional aggregation of acetylcholine receptors, acetylcholine cannot cause muscle fiber activity, thereby reducing muscle contraction and facial expressions
机理
集聚蛋白（agrin）-肌特异性激酶(MuSK )-缔合蛋白(rapsyn)-乙酰胆碱受体(AchR)稳定有序的串联在一起是神经肌肉连接形成的核心。突触运动神经元释放的集聚蛋白可以使MuSK聚集在一起。乙酰基六肽-30阻止集聚蛋白和肌特异性激酶（MuSK）结合，因此MuSK不能激活以及乙酰胆碱受体β组未被磷酸化，而这两步都是乙酰胆碱受体功能性集聚所必须的。由于乙酰胆碱受体功能性集聚被阻止，乙酰胆碱无法引起肌纤维活动，因此降低肌肉收缩，减少表情纹。
The stable and orderly concatenation of aggrin muscle specific kinase (MuSK) associated protein (rapsyn) acetylcholine receptor (AchR) is the core of the formation of neuromuscular connections. The aggregation proteins released by synaptic motor neurons can cause MuSK to aggregate together. Acetylhexapeptide-30 prevents aggregation protein from binding to muscle specific kinase (MuSK), therefore MuSK cannot be activated and acetylcholine receptors cannot be activated β The group is not phosphorylated, and both steps are necessary for the functional aggregation of acetylcholine receptors. Due to the blocking of functional aggregation of acetylcholine receptors, acetylcholine cannot cause muscle fiber activity, thereby reducing muscle contraction and facial expressions
